. "Edited: D'Eustachio, P, 2009-08-20"^^ . "Reviewed: Jassal, B, 2009-08-20"^^ . "Reviewed: Hannun, YA, Luberto, C, 2009-11-18"^^ . "Authored: D'Eustachio, P, 2009-08-20"^^ . "ACER1 (alkaline ceramidase 1), associated with the endoplasmic reticulum membrane, catalyzes the reversible hydrolysis of ceramide to yield a free fatty acid (annotated here as stearate) and sphingosine (Sun et al. 2008)."^^ . . . . . . "ceramide + H2O <=> stearate + sphingosine [endoplasmic reticulum]"^^ . "3.5.1.23"^^ . . . . . . . .