. "Authored: Jassal, B, 2007-01-24 15:15:12"^^ . "Reviewed: D'Eustachio, P, 2007-01-22 01:32:07"^^ . "Lanosterol synthase (LS) catalyzes the cyclization of squalene 2,3-epoxide to lanosterol, a reaction that forms the sterol nucleus.LS is located on the ER membrane and is active as the monomer (Ruf et al, 2004)."^^ . . . . . . . . "Squalene 2,3-epoxide cyclizes, forming lanosterol"^^ . "5.4.99.7"^^ . . . . . .