. "Authored: Gillespie, ME, 2009-08-27"^^ . "Edited: Gillespie, ME, 2008-05-21 20:31:35"^^ . "Reviewed: Simpson, JC, 2009-08-27"^^ . "Once the basic components of the docking complex are assembled with one end of AP-1 bound to cargo molecules, the other end binds to clathrin. Clathrin triskelions polymerize into hexagons and pentagons, forming a cage, which leads to membrane deformation. This polymerization step drives the sculpting of the lysosome vesicle. Here only 5 clathrin triskelions are represented, though in reality many more would be involved in sculpting an entire vesicle."^^ . . . . . . . "trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly"^^ . . . . . . . . . . . . . .