. "Reviewed: D'Eustachio, P, 2010-05-21"^^ . "Edited: Jupe, S, 2010-05-26"^^ . "Authored: Jupe, S, 2010-05-18"^^ . "The classical view of G-protein signalling is that the G-protein alpha subunit dissociates from the beta:gamma dimer. Activated G alpha (z) and the beta:gamma dimer then participate in separate signaling cascades. Although G protein dissociation has been contested (e.g. Bassi et al. 1996), recent in vivo experiments have demonstrated that dissociation does occur, though possibly not to completion (Lambert 2008)."^^ . . . . . . . "The Ligand:GPCR:Gz complex dissociates"^^ . . . . . . . .