. "Reviewed: Antonellis, A, 2008-12-02 16:58:45"^^ . "Authored: D'Eustachio, P, 2008-11-29 15:41:00"^^ . "Edited: D'Eustachio, P, 2008-11-29 15:41:00"^^ . "Multifunctional EPRS (cytosolic glutamyl-prolyl tRNA synthetase) catalyzes the reaction of proline, tRNA(Pro), and ATP to form Pro-tRNA(Pro), AMP, and pyrophosphate. The same enzyme also catalyzes the charging of tRNA(Glu) with glutamate. The enzyme is found in the cell as a component of the mutienzyme aminoacyl-tRNA synthetase complex (Kaiser et al. 1994)."^^ . . . . . . "proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate"^^ . "6.1.1.15"^^ . . . . . . . . . .