. "Authored: Rudd, C.E., de Bono, B, Garapati, P V, 2008-01-24 15:53:10"^^ . "Reviewed: Trowsdale, J, 2008-02-26 12:02:59"^^ . "PTEN dephosphorylates 3' position of PIP3 to generate PIP2 and negatively regulates the PI3K pathway and PKB activation."^^ . . . . . "Hydrolysis of PIP3 to PIP2"^^ . "3.1.3.67"^^ . . . . . . .