. "This is the first component of the elongase, a microsomal protein complex responsible for extending palmitoyl-CoA and stearoyl-CoA (and modified forms thereof) to very-long-chain acyl CoAs." . "Multiple forms exist with differing preferences for the substrate, and thus the specific form expressed determines the local composition of very-long-chain fatty acids." . "For example, the FAE1 form from the plant Arabidopsis thaliana accepts only 16 and 18 carbon substrates, with oleoyl-CoA (18:1) being the preferred substrate, while CER6 from the same plant prefers substrates with chain length of C(22) to C(32)." . "Cf. EC 1.1.1.330, EC 4.2.1.134 and EC 1.3.1.93." . . . "Condensing enzyme" . "Very-long-chain 3-oxoacyl-CoA synthase" . "Very-long-chain 3-ketoacyl-CoA synthase" . "Very-long-chain beta-ketoacyl-CoA synthase" . . "A very-long-chain acyl-CoA + malonyl-CoA = CoA + a very-long-chain 3-oxoacyl-CoA + CO(2)." . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .