. "\"A series of reactions in which a signal is passed on to downstream proteins within the cell by sequential protein phosphorylation and activation of the cascade components.\" [GOC:bf, GOC:jl, GOC:signaling]" . . "intracellular protein kinase cascade" . "protein kinase cascade" . "Reactome:REACT_100795 \"PKA-mediated phosphorylation of key metabolic factors, Saccharomyces cerevisiae\"" . "Reactome:REACT_102462 \"PKA-mediated phosphorylation of key metabolic factors, Canis familiaris\"" . "Reactome:REACT_104200 \"PKA-mediated phosphorylation of key metabolic factors, Taeniopygia guttata\"" . "Reactome:REACT_108216 \"PKA-mediated phosphorylation of key metabolic factors, Dictyostelium discoideum\"" . "Reactome:REACT_1525 \"PKA-mediated phosphorylation of key metabolic factors, Homo sapiens\"" . "Reactome:REACT_80030 \"PKA-mediated phosphorylation of key metabolic factors, Sus scrofa\"" . "Reactome:REACT_83068 \"PKA-mediated phosphorylation of key metabolic factors, Gallus gallus\"" . "Reactome:REACT_83869 \"PKA-mediated phosphorylation of key metabolic factors, Xenopus tropicalis\"" . "Reactome:REACT_87453 \"PKA-mediated phosphorylation of key metabolic factors, Bos taurus\"" . "Reactome:REACT_89085 \"PKA-mediated phosphorylation of key metabolic factors, Rattus norvegicus\"" . "Reactome:REACT_89983 \"PKA-mediated phosphorylation of key metabolic factors, Danio rerio\"" . "Reactome:REACT_90740 \"PKA-mediated phosphorylation of key metabolic factors, Schizosaccharomyces pombe\"" . "Reactome:REACT_99938 \"PKA-mediated phosphorylation of key metabolic factors, Mus musculus\"" . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .