. "\"Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate.\" [EC:4.6.1.1]" . . "adenylate cyclase activity" . "3',5'-cyclic AMP synthetase activity" . "adenyl cyclase activity" . "adenylyl cyclase activity" . "adenylylcyclase activity" . "ATP diphosphate-lyase (cyclizing) activity" . "ATP diphosphate-lyase (cyclizing; 3',5'-cyclic-AMP-forming) activity" . "ATP pyrophosphate-lyase activity" . "EC:4.6.1.1" . "MetaCyc:ADENYLATECYC-RXN" . "Reactome:REACT_101083 \"Activated Adenylate cyclase catalyses cAMP synthesis, Gallus gallus\"" . "Reactome:REACT_103498 \"Production of Cyclic AMP by Activated Adenylyl Cyclase, Sus scrofa\"" . "Reactome:REACT_104211 \"Adenylate cyclase converts ATP into cyclic AMP, Drosophila melanogaster\"" . "Reactome:REACT_106348 \"Activated Adenylate cyclase catalyses cAMP synthesis, Taeniopygia guttata\"" . "Reactome:REACT_110132 \"Production of Cyclic AMP by Activated Adenylyl Cyclase, Bos taurus\"" . "Reactome:REACT_110346 \"Adenylate cyclase converts ATP into cyclic AMP, Caenorhabditis elegans\"" . "Reactome:REACT_114273 \"Production of Cyclic AMP by Activated Adenylyl Cyclase, Xenopus tropicalis\"" . "Reactome:REACT_114694 \"Production of Cyclic AMP by Activated Adenylyl Cyclase, Drosophila melanogaster\"" . "Reactome:REACT_1292 \"Activated Adenylate cyclase catalyses cAMP synthesis, Homo sapiens\"" . "Reactome:REACT_15399 \"Adenylate cyclase converts ATP into cyclic AMP, Homo sapiens\"" . "Reactome:REACT_18321 \"Production of Cyclic AMP by Activated Adenylyl Cyclase, Homo sapiens\"" . "Reactome:REACT_19249 \"Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate, Homo sapiens\"" . "Reactome:REACT_19407 \"Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate, Canis familiaris\"" . "Reactome:REACT_20564 \"Activation of Adenylate Cyclase, Homo sapiens\"" . "Reactome:REACT_28885 \"Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate, Bos taurus\"" . "Reactome:REACT_28984 \"Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate, Caenorhabditis elegans\"" . "Reactome:REACT_30072 \"Production of Cyclic AMP by Activated Adenylyl Cyclase, Danio rerio\"" . "Reactome:REACT_30354 \"Activated Adenylate cyclase catalyses cAMP synthesis, Caenorhabditis elegans\"" . "Reactome:REACT_32296 \"Adenylate cyclase converts ATP into cyclic AMP, Bos taurus\"" . "Reactome:REACT_77589 \"Activated Adenylate cyclase catalyses cAMP synthesis, Danio rerio\"" . "Reactome:REACT_77648 \"Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate, Danio rerio\"" . "Reactome:REACT_77920 \"Adenylate cyclase converts ATP into cyclic AMP, Canis familiaris\"" . "Reactome:REACT_78464 \"Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate, Taeniopygia guttata\"" . "Reactome:REACT_78878 \"Production of Cyclic AMP by Activated Adenylyl Cyclase, Taeniopygia guttata\"" . "Reactome:REACT_79135 \"Adenylate cyclase converts ATP into cyclic AMP, Mus musculus\"" . "Reactome:REACT_79837 \"Adenylate cyclase converts ATP into cyclic AMP, Taeniopygia guttata\"" . "Reactome:REACT_80253 \"Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate, Drosophila melanogaster\"" . "Reactome:REACT_80404 \"Activated Adenylate cyclase catalyses cAMP synthesis, Mus musculus\"" . "Reactome:REACT_80465 \"Activated Adenylate cyclase catalyses cAMP synthesis, Drosophila melanogaster\"" . "Reactome:REACT_80777 \"Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate, Rattus norvegicus\"" . "Reactome:REACT_81089 \"Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate, Sus scrofa\"" . "Reactome:REACT_81527 \"Production of Cyclic AMP by Activated Adenylyl Cyclase, Canis familiaris\"" . "Reactome:REACT_81605 \"Adenylate cyclase converts ATP into cyclic AMP, Rattus norvegicus\"" . "Reactome:REACT_84068 \"Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate, Mus musculus\"" . "Reactome:REACT_84304 \"Adenylate cyclase converts ATP into cyclic AMP, Gallus gallus\"" . "Reactome:REACT_84639 \"Activated Adenylate cyclase catalyses cAMP synthesis, Canis familiaris\"" . "Reactome:REACT_85469 \"Adenylate cyclase converts ATP into cyclic AMP, Xenopus tropicalis\"" . "Reactome:REACT_85953 \"Adenylate cyclase converts ATP into cyclic AMP, Danio rerio\"" . "Reactome:REACT_86733 \"Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate, Xenopus tropicalis\"" . "Reactome:REACT_87138 \"Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate, Gallus gallus\"" . "Reactome:REACT_92664 \"Production of Cyclic AMP by Activated Adenylyl Cyclase, Mus musculus\"" . "Reactome:REACT_92794 \"Activated Adenylate cyclase catalyses cAMP synthesis, Sus scrofa\"" . "Reactome:REACT_93757 \"Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate, Mycobacterium tuberculosis\"" . "Reactome:REACT_94136 \"Activated Adenylate cyclase catalyses cAMP synthesis, Xenopus tropicalis\"" . "Reactome:REACT_97516 \"Activated Adenylate cyclase catalyses cAMP synthesis, Bos taurus\"" . "RHEA:15392" . . . "cAMP generating peptide activity" . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .