<http://identifiers.org/uniprot/P60880> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.biopax.org/release/biopax-level3.owl#ProteinReference> .
<http://identifiers.org/uniprot/P60880> <http://www.biopax.org/release/biopax-level3.owl#comment> "SEQUENCE 206 AA; 23315 MW; FBED2B082A4CB6A6 CRC64;"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/P60880> <http://www.biopax.org/release/biopax-level3.owl#comment> "FUNCTION: t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. SUBUNIT: Part of the SNARE core complex containing SNAP25, VAMP2 and STX1A. This complex binds CPLX1. Interacts with CENPF, TRIM9, RIMS1, SNAPIN, OTOF and HGS. Binds STXBP6. Found in a ternary complex with STX1A and VAMP8. Found in a complex containing SYT1, SV2B and syntaxin-1 (By similarity). SUBCELLULAR LOCATION: Cytoplasm, perinuclear region (By similarity). Cell membrane; Lipid-anchor. Cell junction, synapse, synaptosome. Note=Membrane association requires palmitoylation. Expressed throughout cytoplasm, concentrating at the perinuclear region (By similarity). ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=2; Comment=Isoforms differ by the usage of two alternative homologous exons (5a and 5b) which encode for positions 56 to 94 and differ only in 9 positions out of 39; Name=SNAP-25b; IsoId=P60880-1, P13795-1; Sequence=Displayed; Name=SNAP-25a; IsoId=P60880-2, P13795-2; Sequence=VSP_006186; TISSUE SPECIFICITY: Neurons of the neocortex, hippocampus, piriform cortex, anterior thalamic nuclei, pontine nuclei, and granule cells of the cerebellum. PTM: Palmitoylated. Cys-85 appears to be the main site, and palmitoylation is required for membrane association (By similarity). MISCELLANEOUS: When cloned and expressed in Eschericia coli, where protein palmitoylation does not occur, Cys-85, Cys-88, Cys-90 and Cys-92 in the protein sequence readily form an iron-sulfur cluster instead. SIMILARITY: Belongs to the SNAP-25 family. SIMILARITY: Contains 2 t-SNARE coiled-coil homology domains. GENE SYNONYMS:SNAP25 SNAP. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License."^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/P60880> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:UNIPROT_D3DW16> .
<http://identifiers.org/uniprot/P60880> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:UNIPROT_P36974> .
<http://identifiers.org/uniprot/P60880> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:UNIPROT_P60880> .
<http://identifiers.org/uniprot/P60880> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:RelationshipXref:REFSEQ_NP_570824> .
<http://identifiers.org/uniprot/P60880> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:RelationshipXref:REFSEQ_NP_003072> .
<http://identifiers.org/uniprot/P60880> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:UNIPROT_P70558> .
<http://identifiers.org/uniprot/P60880> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:UNIPROT_Q8IXK3> .
<http://identifiers.org/uniprot/P60880> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:RelationshipXref:HGNC_HGNC%3A11132> .
<http://identifiers.org/uniprot/P60880> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:UNIPROT_Q53EM2> .
<http://identifiers.org/uniprot/P60880> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:UNIPROT_B2RAU4> .
<http://identifiers.org/uniprot/P60880> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:UNIPROT_Q5U0B5> .
<http://identifiers.org/uniprot/P60880> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:UNIPROT_P70557> .
<http://identifiers.org/uniprot/P60880> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:RelationshipXref:NCBI+GENE_6616> .
<http://identifiers.org/uniprot/P60880> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:UNIPROT_D3DW17> .
<http://identifiers.org/uniprot/P60880> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:UNIPROT_P13795> .
<http://identifiers.org/uniprot/P60880> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:UNIPROT_Q96FM2> .
<http://identifiers.org/uniprot/P60880> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:UNIPROT_Q9BR45> .
<http://identifiers.org/uniprot/P60880> <http://www.biopax.org/release/biopax-level3.owl#displayName> "SNP25_HUMAN"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/P60880> <http://www.biopax.org/release/biopax-level3.owl#name> "SNAP-25"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/P60880> <http://www.biopax.org/release/biopax-level3.owl#name> "Super protein"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/P60880> <http://www.biopax.org/release/biopax-level3.owl#name> "SUP"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/P60880> <http://www.biopax.org/release/biopax-level3.owl#name> "Synaptosomal-associated 25 kDa protein"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/P60880> <http://www.biopax.org/release/biopax-level3.owl#name> "SNAP25"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/P60880> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:SNP25_HUMAN_1> .
<http://identifiers.org/uniprot/P60880> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:SNP25_HUMAN_2> .
<http://identifiers.org/uniprot/P60880> <http://www.biopax.org/release/biopax-level3.owl#organism> <http://identifiers.org/taxonomy/9606> .
<http://identifiers.org/uniprot/P60880> <http://www.biopax.org/release/biopax-level3.owl#sequence> "MAEDADMRNELEEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLERIEEGMDQINKDMKEAEKNLTDLGKFCGLCVCPCNKLKSSDAYKKAWGNNQDGVVASQPARVVDEREQMAISGGFIRRVTNDARENEMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQRATKMLGSG"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/P60880> <http://www.biopax.org/release/biopax-level3.owl#standardName> "Synaptosomal-associated protein 25"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://pid.nci.nih.gov/biopaxpid_2227> <http://www.biopax.org/release/biopax-level3.owl#entityReference> <http://identifiers.org/uniprot/P60880> .
<http://pid.nci.nih.gov/biopaxpid_2162> <http://www.biopax.org/release/biopax-level3.owl#entityReference> <http://identifiers.org/uniprot/P60880> .
<http://www.reactome.org/biopax/48887Protein6682> <http://www.biopax.org/release/biopax-level3.owl#entityReference> <http://identifiers.org/uniprot/P60880> .
<HTTP://PATHWAYCOMMONS.ORG/PSI2BP#_2637> <http://www.biopax.org/release/biopax-level3.owl#entityReference> <http://identifiers.org/uniprot/P60880> .
<http://www.reactome.org/biopax/48887Protein6692> <http://www.biopax.org/release/biopax-level3.owl#entityReference> <http://identifiers.org/uniprot/P60880> .
<http://pid.nci.nih.gov/biopaxpid_165124> <http://www.biopax.org/release/biopax-level3.owl#entityReference> <http://identifiers.org/uniprot/P60880> .
<http://pid.nci.nih.gov/biopaxpid_165405> <http://www.biopax.org/release/biopax-level3.owl#entityReference> <http://identifiers.org/uniprot/P60880> .
<http://www.reactome.org/biopax/48887Protein6685> <http://www.biopax.org/release/biopax-level3.owl#entityReference> <http://identifiers.org/uniprot/P60880> .
<http://pid.nci.nih.gov/biopaxpid_165132> <http://www.biopax.org/release/biopax-level3.owl#entityReference> <http://identifiers.org/uniprot/P60880> .
<http://www.reactome.org/biopax/48887Protein6683> <http://www.biopax.org/release/biopax-level3.owl#entityReference> <http://identifiers.org/uniprot/P60880> .
<http://pid.nci.nih.gov/biopaxpid_165211> <http://www.biopax.org/release/biopax-level3.owl#entityReference> <http://identifiers.org/uniprot/P60880> .
<http://pid.nci.nih.gov/biopaxpid_165415> <http://www.biopax.org/release/biopax-level3.owl#entityReference> <http://identifiers.org/uniprot/P60880> .
<http://www.reactome.org/biopax/48887Protein6691> <http://www.biopax.org/release/biopax-level3.owl#entityReference> <http://identifiers.org/uniprot/P60880> .
<http://pid.nci.nih.gov/biopaxpid_165128> <http://www.biopax.org/release/biopax-level3.owl#entityReference> <http://identifiers.org/uniprot/P60880> .
<http://www.reactome.org/biopax/48887Protein6686> <http://www.biopax.org/release/biopax-level3.owl#entityReference> <http://identifiers.org/uniprot/P60880> .
<http://www.reactome.org/biopax/48887Protein6689> <http://www.biopax.org/release/biopax-level3.owl#entityReference> <http://identifiers.org/uniprot/P60880> .
<http://www.reactome.org/biopax/48887Protein6688> <http://www.biopax.org/release/biopax-level3.owl#entityReference> <http://identifiers.org/uniprot/P60880> .
<http://www.phosphosite.org/phosphosite.owl#ModifiedProtein_5147> <http://www.biopax.org/release/biopax-level3.owl#entityReference> <http://identifiers.org/uniprot/P60880> .
<http://www.phosphosite.org/phosphosite.owl#Protein_2038> <http://www.biopax.org/release/biopax-level3.owl#entityReference> <http://identifiers.org/uniprot/P60880> .
<http://www.pantherdb.org/pathways/biopax#_SNARE_br_Complex_PROTEIN> <http://www.biopax.org/release/biopax-level3.owl#memberEntityReference> <http://identifiers.org/uniprot/P60880> .
<http://www.pantherdb.org/pathways/biopax#_SNAP_25_PROTEIN> <http://www.biopax.org/release/biopax-level3.owl#memberEntityReference> <http://identifiers.org/uniprot/P60880> .
<http://www.pantherdb.org/pathways/biopax#_SNARE_PROTEIN> <http://www.biopax.org/release/biopax-level3.owl#memberEntityReference> <http://identifiers.org/uniprot/P60880> .
<http://www.pantherdb.org/pathways/biopax#_SNARE_Complex_PROTEIN> <http://www.biopax.org/release/biopax-level3.owl#memberEntityReference> <http://identifiers.org/uniprot/P60880> .