Source:http://linkedlifedata.com/resource/umls/id/C1307637
NCI: Encoded by human UBE2D2 Gene (E2 Ubiquitin-Conjugating Enzyme Family), 147-aa 16.7-kDa Ubiquitin-Conjugating Enzyme E2D 2 targets selective degradation of short-lived and abnormal proteins, such as E6/E6-AP-induced p53 ubiquitination, through covalent attachment of ubiquitin, the second step of ubiquitin conjugation. UBE2D2 interacts with the SCF/E3 ubiquitin ligase complex. Ubiquitination involves E1 ubiquitin-activating enzymes, E2 ubiquitin-conjugating enzymes, and E3 ubiquitin-protein ligases. (NCI)