Source:http://linkedlifedata.com/resource/umls/id/C0338508
MSH: Dominant optic atrophy is a hereditary optic neuropathy causing decreased visual acuity, color vision deficits, a centrocecal scotoma, and optic nerve pallor (Hum. Genet. 1998; 102: 79-86). Mutations leading to this condition have been mapped to the OPA1 gene at chromosome 3q28-q29. OPA1 codes for a dynamin-related GTPase that localizes to mitochondria.,NCI: An autosomal dominant hereditary condition characterized by optic atrophy and progressive visual loss.