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skos:definition |
JABL: Fetal abnormalities due to the maternal use of valproic acid in anticonvulsant therapy of epilepsy during pregnancy. Common craniofacial anomalies include epicanthal folds, broad nose with a flat bridge, anterverted nostrils, shallow philtrum, a thin upper and thick lower lip. Associated disorders may include developmental delay, neurologic abnormalities congenital heart defects, finger abnormalities, and other defects.,NCI: A rare syndrome caused by exposure of the fetus to valproic acid in the first three months of the pregnancy. It is characterized by musculoskeletal abnormalities, intellectual disability, spina bifida, and distinctive facial features.
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