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MSH: A chronic inflammatory condition affecting the axial joints, such as the SACROILIAC JOINT and other intervertebral or costovertebral joints. It occurs predominantly in young males and is characterized by pain and stiffness of joints (ANKYLOSIS) with inflammation at tendon insertions.,MEDLINEPLUS: <p>Ankylosing spondylitis is a type of <a href='http://www.nlm.nih.gov/medlineplus/arthritis.html'>arthritis</a> of the spine. It causes swelling between your vertebrae, which are the disks that make up your spine, and in the joints between your spine and pelvis. Ankylosing spondylitis is an <a href='http://www.nlm.nih.gov/medlineplus/immunesystemanddisorders.html'>immune disease</a>. The disease is more common and more severe in men. It often runs in families. </p><p>Early symptoms include back pain and stiffness. These problems often start in late adolescence or early adulthood. Over time, ankylosing spondylitis can fuse your vertebrae together, limiting movement. Symptoms can worsen or improve or stop altoget
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