Nifedipine

Source:http://linkedlifedata.com/resource/umls/id/C0028066

MSH: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.,CSP: calcium channel blocker used as a coronary vasodilator in the treatment of coronary insufficiency and angina.,CHV: a drug used for hypertension,NCI: A dihydropyridine calcium channel blocking agent. Nifedipine inhibits the transmembrane influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, causing dilatation of the main coronary and systemic arteries and decreasing myocardial contractility. This agent also inhibits the drug efflux pump P-glycoprotein which is overexpressed in some multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents. (NCI04)

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