Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| calbc:hasCorrelation | |
| skos:definition |
NCI: Human IKZF1 wild-type allele is located within 7p13-p11.1 and is approximately 123 kb in length. This allele, which encodes DNA-binding protein Ikaros, plays a role in transcriptional enhancement. Truncated and mutated forms of the gene can be a factor in acute lymphoblastic leukemia. A translocation t(3;7)(q27;p12) that fuses the gene to the BCL6 gene is implicated in diffuse large B-cell lymphomas. (OMIM)
|
| skos:inScheme | |
| skos-xl:prefLabel | |
| skos-xl:altLabel |