TSC1-TSC2 complex location

Source:http://linkedlifedata.com/resource/umls/id/C2247022

GO: A heterodimeric protein complex consisting of tumerin and hamartin; its formation may regulate hamartin homomultimer formation. The complex acts as a GTPase activating protein (GAP) for the small GTPase (Rheb), and inhibits the TOR signaling pathway. [PMID:10585443, PMID:17121544, PMID:9580671]

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