immunophilin activity

Source:http://linkedlifedata.com/resource/umls/id/C1325342

GO: OBSOLETE. Any member of a family of receptors that includes the major FK506 binding protein FKBP and cyclophilin. These two proteins are unrelated in amino-acid sequence, but both possess peptidyl-prolyl isomerase activity which is blocked by immunosuppressants that block signal-transduction pathways leading to T cell activation such as FK506 and rapamycin, which block FKBP, or cyclosporin A, which blocks cyclophilin. [ISBN:0198506732]

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