@prefix activity: <http://linkedlifedata.com/resource/chembl/activity/> .
@prefix address: <http://linkedlifedata.com/resource/clinicaltrials/address/> .
@prefix agency: <http://linkedlifedata.com/resource/clinicaltrials/agency/> .
@prefix assay: <http://linkedlifedata.com/resource/chembl/assay/> .
@prefix assayCategory: <http://linkedlifedata.com/resource/chembl/assayCategory/> .
@prefix assayTargetLink: <http://linkedlifedata.com/resource/chembl/assayTargetLink/> .
@prefix biopax3: <http://www.biopax.org/release/biopax-level3.owl#> .
@prefix calbc: <http://linkedlifedata.com/resource/calbc/> .
@prefix calbc-group: <http://linkedlifedata.com/resource/calbc/group/> .
@prefix carrierLink: <http://linkedlifedata.com/resource/drugbank/carrierLink/> .
@prefix certainAgreement: <http://linkedlifedata.com/resource/clinicaltrials/certainAgreement/> .
@prefix chebi: <http://linkedlifedata.com/resource/chebi/id/> .
@prefix chembl: <http://linkedlifedata.com/resource/chembl/> .
@prefix chemicalCompound: <http://linkedlifedata.com/resource/chembl/compound/> .
@prefix chemicalCompoundRecord: <http://linkedlifedata.com/resource/chembl/chemicalCompoundRecord/> .
@prefix clan: <http://linkedlifedata.com/resource/pfam/clan/> .
@prefix clinicalResult: <http://linkedlifedata.com/resource/clinicaltrials/clinicalResult/> .
@prefix clinicalStudy: <http://linkedlifedata.com/resource/clinicaltrials/study/> .
@prefix clinicaltrials: <http://linkedlifedata.com/resource/clinicaltrials/> .
@prefix company: <http://linkedlifedata.com/resource/chembl/company/> .
@prefix confidenceScore: <http://linkedlifedata.com/resource/chembl/confidenceScore/> .
@prefix contact: <http://linkedlifedata.com/resource/clinicaltrials/contact/> .
@prefix country: <http://linkedlifedata.com/resource/chembl/country/> .
@prefix cpath: <http://cbio.mskcc.org/cpath#> .
@prefix curationLookup: <http://linkedlifedata.com/resource/chembl/curationLookup/> .
@prefix dailymed: <http://www4.wiwiss.fu-berlin.de/dailymed/resource/> .
@prefix dailymed-drugs: <http://www4.wiwiss.fu-berlin.de/dailymed/resource/drugs/> .
@prefix dailymed-ingredient: <http://www4.wiwiss.fu-berlin.de/dailymed/resource/ingredient/> .
@prefix dailymed-instance: <http://www4.wiwiss.fu-berlin.de/dailymed/resource/dailymed/> .
@prefix databaseReference: <http://linkedlifedata.com/resource/pfam/databaseReference/> .
@prefix dc: <http://purl.org/dc/elements/1.1/> .
@prefix dc-term: <http://purl.org/dc/terms/> .
@prefix diseaseontology: <http://linkedlifedata.com/resource/diseaseontology/id/> .
@prefix diseasome: <http://www4.wiwiss.fu-berlin.de/diseasome/resource/> .
@prefix diseasome-diseases: <http://www4.wiwiss.fu-berlin.de/diseasome/resource/diseases/> .
@prefix diseasome-gene: <http://www4.wiwiss.fu-berlin.de/diseasome/resource/genes/> .
@prefix diseasome-instance: <http://www4.wiwiss.fu-berlin.de/diseasome/resource/diseasome/> .
@prefix documentType: <http://linkedlifedata.com/resource/chembl/documentType/> .
@prefix dosageForm: <http://linkedlifedata.com/resource/drugbank/dosageForm/> .
@prefix drug: <http://linkedlifedata.com/resource/drugbank/drug/> .
@prefix drugbank: <http://linkedlifedata.com/resource/drugbank/> .
@prefix drugbank-proteinSequence: <http://linkedlifedata.com/resource/drugbank/proteinSequence/> .
@prefix drugCategory: <http://linkedlifedata.com/resource/drugbank/drugCategory/> .
@prefix drugInteraction: <http://linkedlifedata.com/resource/drugbank/drugInteraction/> .
@prefix drugTarget: <http://linkedlifedata.com/resource/chembl/drugTarget/> .
@prefix eligibility: <http://linkedlifedata.com/resource/clinicaltrials/eligibility/> .
@prefix entrez-gene: <http://linkedlifedata.com/resource/entrezgene/id/> .
@prefix entrez-goterm: <http://linkedlifedata.com/resource/entrezgene/goterm/> .
@prefix entrezgene: <http://linkedlifedata.com/resource/entrezgene/> .
@prefix enzymeLink: <http://linkedlifedata.com/resource/drugbank/enzymeLink/> .
@prefix externalIdentifier: <http://linkedlifedata.com/resource/drugbank/externalIdentifier/> .
@prefix externalLink: <http://linkedlifedata.com/resource/drugbank/externalLink/> .
@prefix factforge: <http://factforge.net/> .
@prefix family: <http://linkedlifedata.com/resource/pfam/family/> .
@prefix foaf: <http://xmlns.com/foaf/0.1/> .
@prefix formulation: <http://linkedlifedata.com/resource/chembl/formulation/> .
@prefix freebase: <http://rdf.freebase.com/ns/> .
@prefix gene-rif: <http://linkedlifedata.com/resource/entrezgene/generif/> .
@prefix geneontology: <http://linkedlifedata.com/resource/geneontology/> .
@prefix geneSequence: <http://linkedlifedata.com/resource/drugbank/geneSequence/> .
@prefix hapmap: <http://linkedlifedata.com/resource/hapmap/> .
@prefix indication: <http://linkedlifedata.com/resource/sider/indication/> .
@prefix intervention: <http://linkedlifedata.com/resource/clinicaltrials/intervention/> .
@prefix investigator: <http://linkedlifedata.com/resource/clinicaltrials/investigator/> .
@prefix label: <http://linkedlifedata.com/resource/sider/label/> .
@prefix lhgdn: <http://linkedlifedata.com/resource/lhgdn/> .
@prefix lifeskim: <http://linkedlifedata.com/resource/lifeskim/> .
@prefix linkedct: <http://data.linkedct.org/resource/linkedct/> .
@prefix linkedct-condition: <http://data.linkedct.org/resource/condition/> .
@prefix linkedct-intervention: <http://data.linkedct.org/resource/intervention/> .
@prefix literatureCitation: <http://linkedlifedata.com/resource/drugbank/citation/> .
@prefix lld: <http://linkedlifedata.com/resource/> .
@prefix location: <http://linkedlifedata.com/resource/clinicaltrials/location/> .
@prefix measurement: <http://linkedlifedata.com/resource/clinicaltrials/measurement/> .
@prefix meddraSideEffect: <http://linkedlifedata.com/resource/sider/meddraSideEffect/> .
@prefix mixture: <http://linkedlifedata.com/resource/drugbank/mixture/> .
@prefix molecularSpecies: <http://linkedlifedata.com/resource/chembl/molecularSpecies/> .
@prefix molecule: <http://linkedlifedata.com/resource/drugbank/molecule/> .
@prefix moleculeType: <http://linkedlifedata.com/resource/chembl/moleculeType/> .
@prefix ontotext: <http://www.ontotext.com/> .
@prefix organismSpecies: <http://linkedlifedata.com/resource/drugbank/organismSpecies/> .
@prefix outcomeAnalysis: <http://linkedlifedata.com/resource/clinicaltrials/outcomeAnalysis/> .
@prefix outcomeMeasure: <http://linkedlifedata.com/resource/clinicaltrials/outcomeMeasure/> .
@prefix overallOfficial: <http://linkedlifedata.com/resource/clinicaltrials/overallOfficial/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix owlim: <http://www.ontotext.com/owlim/> .
@prefix packager: <http://linkedlifedata.com/resource/drugbank/packager/> .
@prefix participantFlow: <http://linkedlifedata.com/resource/clinicaltrials/participantFlow/> .
@prefix patent: <http://linkedlifedata.com/resource/drugbank/patent/> .
@prefix pfam: <http://linkedlifedata.com/resource/pfam/> .
@prefix phenotype: <http://linkedlifedata.com/resource/phenotype/id/> .
@prefix pointOfContact: <http://linkedlifedata.com/resource/clinicaltrials/pointOfContact/> .
@prefix price: <http://linkedlifedata.com/resource/drugbank/price/> .
@prefix primaryOutcome: <http://linkedlifedata.com/resource/clinicaltrials/primaryOutcome/> .
@prefix product: <http://linkedlifedata.com/resource/chembl/informationSource/> .
@prefix property: <http://linkedlifedata.com/resource/drugbank/property/> .
@prefix proteinSequence: <http://linkedlifedata.com/resource/pfam/proteinSequence/> .
@prefix pubmed: <http://linkedlifedata.com/resource/pubmed/> .
@prefix pubmed-article: <http://linkedlifedata.com/resource/pubmed/id/> .
@prefix pubmed-author: <http://linkedlifedata.com/resource/pubmed/author/> .
@prefix pubmed-mesh: <http://linkedlifedata.com/resource/pubmed/mesh/> .
@prefix pubmed-meshheading: <http://linkedlifedata.com/resource/pubmed/meshheading/> .
@prefix pubmed-qualifier: <http://linkedlifedata.com/resource/pubmed/qualifier/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix relationshipType: <http://linkedlifedata.com/resource/chembl/relationshipType/> .
@prefix relontology: <http://linkedlifedata.com/resource/relationontology/> .
@prefix reportingGroup: <http://linkedlifedata.com/resource/clinicaltrials/reportingGroup/> .
@prefix researchStem: <http://linkedlifedata.com/resource/chembl/researchStem/> .
@prefix responsibleParty: <http://linkedlifedata.com/resource/clinicaltrials/responsibleParty/> .
@prefix result: <http://linkedlifedata.com/resource/clinicaltrials/result/> .
@prefix resultsBaseline: <http://linkedlifedata.com/resource/clinicaltrials/resultsBaseline/> .
@prefix resultsMeasure: <http://linkedlifedata.com/resource/clinicaltrials/resultsMeasure/> .
@prefix resultsOutcome: <http://linkedlifedata.com/resource/clinicaltrials/outcome/> .
@prefix secondaryOutcome: <http://linkedlifedata.com/resource/clinicaltrials/secondaryOutcome/> .
@prefix sideEffect: <http://linkedlifedata.com/resource/sider/sideEffect/> .
@prefix sideEffectFrequency: <http://linkedlifedata.com/resource/sider/sideEffectFrequency/> .
@prefix sider: <http://linkedlifedata.com/resource/sider/> .
@prefix sider-drug: <http://linkedlifedata.com/resource/sider/drug/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix skos-xl: <http://www.w3.org/2008/05/skos-xl#> .
@prefix snp: <http://linkedlifedata.com/resource/hapmap/snp/> .
@prefix structureType: <http://linkedlifedata.com/resource/chembl/structureType/> .
@prefix studyMilestone: <http://linkedlifedata.com/resource/clinicaltrials/studyMilestone/> .
@prefix studyParticipants: <http://linkedlifedata.com/resource/clinicaltrials/studyParticipants/> .
@prefix studyPeriod: <http://linkedlifedata.com/resource/clinicaltrials/studyPeriod/> .
@prefix substructure: <http://linkedlifedata.com/resource/drugbank/substructure/> .
@prefix symptom: <http://linkedlifedata.com/resource/symptom/id/> .
@prefix synonym: <http://linkedlifedata.com/resource/chembl/synonym/> .
@prefix targetLink: <http://linkedlifedata.com/resource/drugbank/targetLink/> .
@prefix targetType: <http://linkedlifedata.com/resource/chembl/targetType/> .
@prefix taxonomy: <http://linkedlifedata.com/resource/drugbank/taxonomy/> .
@prefix taxonomyClass: <http://linkedlifedata.com/resource/drugbank/taxonomyClass/> .
@prefix taxonomyKingdom: <http://linkedlifedata.com/resource/drugbank/taxonomyKingdom/> .
@prefix transporterLink: <http://linkedlifedata.com/resource/drugbank/transporterLink/> .
@prefix umls: <http://linkedlifedata.com/resource/umls/> .
@prefix umls-concept: <http://linkedlifedata.com/resource/umls/id/> .
@prefix umls-label: <http://linkedlifedata.com/resource/umls/label/> .
@prefix umls-semnetwork: <http://linkedlifedata.com/resource/semanticnetwork/id/> .
@prefix uniprot: <http://purl.uniprot.org/core/> .
@prefix uniprot-protein: <http://purl.uniprot.org/uniprot/> .
@prefix uniprot-unstable: <http://linkedlifedata.com/resource/uniprot#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

umls-concept:C0376358 a umls-semnetwork:T191 , skos:Concept ;
	calbc:hasCorrelation calbc-group:LIVB , calbc-group:ANAT , calbc-group:DISO , calbc-group:GENE , calbc-group:PHYS , calbc-group:ACTI , calbc-group:PROC , calbc-group:OBJC , calbc-group:DEVI , calbc-group:CONC , calbc-group:OCCU , calbc-group:ORGA , calbc-group:CHEM ;
	skos:definition "MEDLINEPLUS: <p>The prostate is the gland below a man's bladder that produces fluid for semen. Prostate cancer is the second most common cause of death from cancer in men of all ages. It is rare in men younger than 40. </p><p>Levels of a substance called prostate specific antigen (PSA) is often high in men with prostate cancer. However, PSA can also be high with other <a href='http://www.nlm.nih.gov/medlineplus/prostatediseases.html'>prostate conditions</a>. Since the PSA test became common, most prostate cancers are found before they cause symptoms. Symptoms of prostate cancer may include</p><ul><li> Problems passing urine, such as pain, difficulty starting or stopping the stream, or dribbling</li><li> Low back pain</li><li> Pain with ejaculation</li></ul><p>Prostate cancer treatment often depends on the stage of the cancer. How fast the cancer grows and how different it is from surrounding tissue helps determine the stage. Treatment may include surgery, radiation therapy, chemotherapy or control of hormones" ;
	skos:inScheme lld:umls ;
	skos:broader umls-concept:C0033578 ;
	skos-xl:prefLabel umls-label:A6840046 ;
	skos-xl:altLabel umls-label:A8343356 , umls-label:A7606010 , umls-label:A18600795 , umls-label:A0996633 , umls-label:A7606231 , umls-label:A7606555 , umls-label:A15661580 , umls-label:A7786660 , umls-label:A0381338 , umls-label:A0381339 , umls-label:A18656548 , umls-label:A4343345 , umls-label:A11976149 , umls-label:A4360734 , umls-label:A12005825 , umls-label:A0667473 , umls-label:A0667472 , umls-label:A0667486 , umls-label:A0777870 , umls-label:A18582145 , umls-label:A18619338 , umls-label:A1638792 , umls-label:A1638793 , umls-label:A0667484 , umls-label:A1057446 , umls-label:A0381342 , umls-label:A4343347 , umls-label:A0890183 , umls-label:A1057447 , umls-label:A0890182 , umls-label:A7606558 , umls-label:A7607011 , umls-label:A7607230 , umls-label:A1412199 ;
	umls:relation <http://linkedlifedata.com/resource/umls/relation/R00746565> , <http://linkedlifedata.com/resource/umls/relation/R00746564> , <http://linkedlifedata.com/resource/umls/relation/R00751606> , <http://linkedlifedata.com/resource/umls/relation/R43993555> , <http://linkedlifedata.com/resource/umls/relation/R43993556> , <http://linkedlifedata.com/resource/umls/relation/R05300943> , <http://linkedlifedata.com/resource/umls/relation/R05303705> , <http://linkedlifedata.com/resource/umls/relation/R05303704> , <http://linkedlifedata.com/resource/umls/relation/R111921172> , <http://linkedlifedata.com/resource/umls/relation/R111878335> , <http://linkedlifedata.com/resource/umls/relation/R111878336> , <http://linkedlifedata.com/resource/umls/relation/R111878334> , <http://linkedlifedata.com/resource/umls/relation/R111921663> , <http://linkedlifedata.com/resource/umls/relation/R41134042> , <http://linkedlifedata.com/resource/umls/relation/R41134043> , 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<http://linkedlifedata.com/resource/umls/relation/R130967233> , <http://linkedlifedata.com/resource/umls/relation/R130967181> , <http://linkedlifedata.com/resource/umls/relation/R130967140> , <http://linkedlifedata.com/resource/umls/relation/R130967201> , <http://linkedlifedata.com/resource/umls/relation/R130967232> , <http://linkedlifedata.com/resource/umls/relation/R130967244> , <http://linkedlifedata.com/resource/umls/relation/R130967154> , <http://linkedlifedata.com/resource/umls/relation/R130967157> , <http://linkedlifedata.com/resource/umls/relation/R130967179> , <http://linkedlifedata.com/resource/umls/relation/R130967172> , <http://linkedlifedata.com/resource/umls/relation/R130967174> , <http://linkedlifedata.com/resource/umls/relation/R130967196> , <http://linkedlifedata.com/resource/umls/relation/R130967160> , <http://linkedlifedata.com/resource/umls/relation/R130967164> , <http://linkedlifedata.com/resource/umls/relation/R130967194> , <http://linkedlifedata.com/resource/umls/relation/R130967158> , <http://linkedlifedata.com/resource/umls/relation/R130967162> , <http://linkedlifedata.com/resource/umls/relation/R130967182> , <http://linkedlifedata.com/resource/umls/relation/R130967256> , <http://linkedlifedata.com/resource/umls/relation/R130967144> , <http://linkedlifedata.com/resource/umls/relation/R130967217> , <http://linkedlifedata.com/resource/umls/relation/R130967159> , <http://linkedlifedata.com/resource/umls/relation/R130967222> , <http://linkedlifedata.com/resource/umls/relation/R130967237> , <http://linkedlifedata.com/resource/umls/relation/R130967243> , <http://linkedlifedata.com/resource/umls/relation/R130967238> , <http://linkedlifedata.com/resource/umls/relation/R111699929> , <http://linkedlifedata.com/resource/umls/relation/R60463993> , <http://linkedlifedata.com/resource/umls/relation/R60466524> , <http://linkedlifedata.com/resource/umls/relation/R60463719> , <http://linkedlifedata.com/resource/umls/relation/R60463718> , <http://linkedlifedata.com/resource/umls/relation/R54360732> , <http://linkedlifedata.com/resource/umls/relation/R54326874> , <http://linkedlifedata.com/resource/umls/relation/R54346888> , <http://linkedlifedata.com/resource/umls/relation/R109444359> , <http://linkedlifedata.com/resource/umls/relation/R109470695> , <http://linkedlifedata.com/resource/umls/relation/R54292135> , <http://linkedlifedata.com/resource/umls/relation/R54292133> , <http://linkedlifedata.com/resource/umls/relation/R54360731> , <http://linkedlifedata.com/resource/umls/relation/R69823080> , <http://linkedlifedata.com/resource/umls/relation/R69805191> , <http://linkedlifedata.com/resource/umls/relation/R69757455> , <http://linkedlifedata.com/resource/umls/relation/R69859063> , <http://linkedlifedata.com/resource/umls/relation/R69848287> , <http://linkedlifedata.com/resource/umls/relation/R69872493> , <http://linkedlifedata.com/resource/umls/relation/R69793967> , <http://linkedlifedata.com/resource/umls/relation/R69812054> , <http://linkedlifedata.com/resource/umls/relation/R69870502> , <http://linkedlifedata.com/resource/umls/relation/R41154043> , <http://linkedlifedata.com/resource/umls/relation/R41154044> , <http://linkedlifedata.com/resource/umls/relation/R41154045> , <http://linkedlifedata.com/resource/umls/relation/R54890823> , <http://linkedlifedata.com/resource/umls/relation/R111901471> , <http://linkedlifedata.com/resource/umls/relation/R111717116> , <http://linkedlifedata.com/resource/umls/relation/R70784388> , <http://linkedlifedata.com/resource/umls/relation/R70872642> , <http://linkedlifedata.com/resource/umls/relation/R70921327> , <http://linkedlifedata.com/resource/umls/relation/R70836474> , <http://linkedlifedata.com/resource/umls/relation/R70941643> , <http://linkedlifedata.com/resource/umls/relation/R70860329> , <http://linkedlifedata.com/resource/umls/relation/R70926957> , <http://linkedlifedata.com/resource/umls/relation/R70832360> , <http://linkedlifedata.com/resource/umls/relation/R70785366> , <http://linkedlifedata.com/resource/umls/relation/R70914173> , <http://linkedlifedata.com/resource/umls/relation/R70806404> , <http://linkedlifedata.com/resource/umls/relation/R40026401> , <http://linkedlifedata.com/resource/umls/relation/R40026405> , <http://linkedlifedata.com/resource/umls/relation/R40026412> , <http://linkedlifedata.com/resource/umls/relation/R40026407> , <http://linkedlifedata.com/resource/umls/relation/R40026410> , <http://linkedlifedata.com/resource/umls/relation/R56496316> , <http://linkedlifedata.com/resource/umls/relation/R125060340> .