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skos:definition |
MSH: Cell-cell junctions that seal adjacent epithelial cells together, preventing the passage of most dissolved molecules from one side of the epithelial sheet to the other. (Alberts et al., Molecular Biology of the Cell, 2nd ed, p22),GO: An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes. [GOC:mah, ISBN:0815332181],CSP: area of closely apposed plasma membranes of two adjacent animal cells; lateral diffusion of proteins within the lipid bilayer is reduced and intercellular exchange of solutes is enhanced.,GO: A cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from on
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