Source:http://linkedlifedata.com/resource/umls/id/C0219806
NCI: Encoded by Receptor Serine/Threonine Kinase Genes, Receptor Serine/Threonine Kinases bind to specific signaling factors causing a conformational and functional change in the ligand-bound receptor, altering its interaction with target molecules, increasing the receptor kinase activity, and leading to changes in cellular physiology through modification of the activity of one or more signal transduction pathways.