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skos:definition |
PDQ: A non-glycosylated recombinant interferon with antiviral and antineoplastic activities. Alfa interferons bind to specific cell-surface receptors, resulting in the transcription and translation of genes whose protein products mediate antiviral, antiproliferative, anticancer, and immune-modulating effects. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=462279&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=462279&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1953" NCI Thesaurus),PDQ: A non-glycosylated recombinant interferon alpha, subtype 2b, used as an antiviral and antineoplastic agent. Alpha interferons bind to specific cell-surface receptors, resulting in the transcription and translation of genes whose protein products mediate antiviral, antiproliferative, anticancer, and immune-modulating effects. Check for "http://www.cancer.gov/
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