Linked Life Data

9889220

Source:http://linkedlifedata.com/resource/pubmed/id/9889220

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1999-2-24
pubmed:abstractText
A new immunochromatographic rapid test, Determine HIV-1/2, for the detection of antibodies to human immunodeficiency virus type 1 (HIV-1) and HIV-2 in human whole blood, serum, and plasma was evaluated. Determine HIV-1/2 is a sandwich immunoassay and uses a nitrocellulose strip with a capture site for the patient's results and a procedural control site to confirm the validity of the assay. The results can be read visually, and a positive result is indicated by the formation of a red line within 15 min after sample application. The test showed 100% sensitivity for HIV-1 with 102 whole-blood, 152 serum, and 144 plasma samples obtained from Ramathibodi Hospital, Bangkok, Thailand. The sensitivity of the test for HIV-2 was 100% with 100 serum or plasma samples obtained from Ivory Coast. The sensitivity of the test with 4 anti-HIV-1 seroconversion panels from Boston Biomedica Inc. was equivalent to or better than those of another agglutination assay with serum or plasma and the enzyme immunoassay licensed by the U.S. Food and Drug Administration. The specificity was 100% with 367 sets of whole-blood, serum, and plasma samples from Ramathibodi Hospital. This method had an analytical sensitivity for the detection of HIV-1 equivalent to or better than that of another agglutination assay with serum or plasma. This test had an analytical sensitivity for the detection of HIV-1 better than that of another immunochromatographic test with whole blood. This evaluation demonstrated the excellent performance of this immunochromatographic test with EDTA-anticoagulated whole-blood, serum, and plasma samples. We conclude that this test is suitable for use in emerging countries and is an excellent alternative to HIV antibody testing at remote sites, as well as in traditional laboratories.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/9889220-1731509, http://linkedlifedata.com/resource/pubmed/commentcorrection/9889220-1760267, http://linkedlifedata.com/resource/pubmed/commentcorrection/9889220-1939584, http://linkedlifedata.com/resource/pubmed/commentcorrection/9889220-2105440, http://linkedlifedata.com/resource/pubmed/commentcorrection/9889220-2425430, http://linkedlifedata.com/resource/pubmed/commentcorrection/9889220-3126752, http://linkedlifedata.com/resource/pubmed/commentcorrection/9889220-3305558, http://linkedlifedata.com/resource/pubmed/commentcorrection/9889220-3340847, http://linkedlifedata.com/resource/pubmed/commentcorrection/9889220-6189183, http://linkedlifedata.com/resource/pubmed/commentcorrection/9889220-6200935, http://linkedlifedata.com/resource/pubmed/commentcorrection/9889220-6200936, http://linkedlifedata.com/resource/pubmed/commentcorrection/9889220-7873345, http://linkedlifedata.com/resource/pubmed/commentcorrection/9889220-7904668
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0095-1137
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
367-70
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Evaluation of a rapid immunochromatographic test for detection of antibodies to human immunodeficiency virus.
pubmed:affiliation
Research and Development Department, Dainabot Co., Ltd., Chiba, Japan. Hiroyasu.Arai@Abbott.com
pubmed:publicationType
Journal Article