Linked Life Data

9813722

Source:http://linkedlifedata.com/resource/pubmed/id/9813722

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1998-11-18
pubmed:abstractText
A follow-up study of a hospital-based population of 166 patients with oral leukoplakia revealed a 2.9% annual malignant transformation rate. The median follow-up period was 29 months. Parameters associated with an increased risk of malignant transformation were female gender (P < 0.025), absence of smoking habits in women (P < 0.05), and a non-homogeneous clinical aspect (P = 0.01). For uniform reporting, a recently proposed classification and staging system has been used. Leukoplakias in stage IV, consisting of lesions with moderate or severe epithelial dysplasia, were associated with an increased risk of malignant transformation (P < 0.01). There were no oral subsites associated with an increased risk. Patients who had any form of intervention did not have a statistically significantly lower chance for malignant transformation than patients who were kept under surveillance without intervention.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1368-8375
pubmed:author
pubmed:issnType
Print
pubmed:volume
34
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
270-5
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Malignant transformation of oral leukoplakia: a follow-up study of a hospital-based population of 166 patients with oral leukoplakia from The Netherlands.
pubmed:affiliation
Department of Oral and Maxillofacial Surgery and Pathology, Academic Hospital Vrije Universiteit/Academic Centre for Dentistry Amsterdam (ACTA), The Netherlands.
pubmed:publicationType
Journal Article