Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1998-9-1
pubmed:abstractText
Current Doppler methods have been unreliable in estimating filling pressures in heart transplants. Tissue Doppler imaging is a technique that permits evaluation of myocardial relaxation; combined with transvalvular E velocity, it could improve estimation of these pressures. To investigate this possibility, we evaluated 50 patients by right-sided cardiac catheterization and Doppler echocardiography simultaneously. Their mean +/-SD age was 53+/-15 years and the mean age of donor hearts was 30+/-12.5 years. The mitral E velocity was combined with the early myocardial relaxation (Ea) velocity by tissue Doppler at the lateral border of the mitral annulus. Likewise, the tricuspid E velocity was combined with Ea at the lateral corner of the tricuspid annulus. Mean wedge pressure related weakly to mitral inflow variables but strongly to E/Ea [r=0.8; wedge pressure=2.6+1.46(E/Ea)]. In 25 repeat right-sided cardiac catheterizations, changes in mean wedge pressure were well detected by Doppler, with a mean difference of -0.7+/-3 mm Hg. Mean right atrial pressure related weakly to routine tricuspid inflow variables but strongly to tricuspid E/Ea [r=0.79; n=38; right atrial pressure=1.76(E/Ea) - 3.7]. In 18 repeat right-sided cardiac catheterizations, changes in mean right atrial pressure were well detected by Doppler, with a mean difference of 0+/-3.45 mm Hg. Mean wedge pressure and mean right atrial pressure can be estimated in heart transplants with reasonable accuracy using the ratio of E/Ea. Furthermore, this method can accurately track changes in filling pressures.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0002-9149
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
82
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
352-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:9708666-Adolescent, pubmed-meshheading:9708666-Adult, pubmed-meshheading:9708666-Aged, pubmed-meshheading:9708666-Echocardiography, Doppler, pubmed-meshheading:9708666-Female, pubmed-meshheading:9708666-Follow-Up Studies, pubmed-meshheading:9708666-Heart Catheterization, pubmed-meshheading:9708666-Heart Transplantation, pubmed-meshheading:9708666-Humans, pubmed-meshheading:9708666-Male, pubmed-meshheading:9708666-Middle Aged, pubmed-meshheading:9708666-Myocardial Contraction, pubmed-meshheading:9708666-Prospective Studies, pubmed-meshheading:9708666-Pulmonary Wedge Pressure, pubmed-meshheading:9708666-Reproducibility of Results, pubmed-meshheading:9708666-Sensitivity and Specificity, pubmed-meshheading:9708666-Ventricular Function, Left, pubmed-meshheading:9708666-Ventricular Function, Right, pubmed-meshheading:9708666-Ventricular Pressure
pubmed:year
1998
pubmed:articleTitle
Estimation of left and right ventricular filling pressures after heart transplantation by tissue Doppler imaging.
pubmed:affiliation
Baylor College of Medicine and Methodist Hospital, Houston, Texas 77030, USA.
pubmed:publicationType
Journal Article, Comparative Study