| pubmed-article:9409741 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9409741 | lifeskim:mentions | umls-concept:C1432126 | lld:lifeskim |
| pubmed-article:9409741 | lifeskim:mentions | umls-concept:C0004083 | lld:lifeskim |
| pubmed-article:9409741 | lifeskim:mentions | umls-concept:C0061421 | lld:lifeskim |
| pubmed-article:9409741 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:9409741 | pubmed:dateCreated | 1998-1-20 | lld:pubmed |
| pubmed-article:9409741 | pubmed:abstractText | Keratin polypeptides 8 and 18 (K8/18) are intermediate filament proteins that are expressed in 'simple-type' epithelial cells. They associate with several proteins including the 70 kDa cytoplasmic heat shock proteins (hsp70). We identified the human 78 kDa glucose-regulated protein (grp78) as a keratin-associated protein. Keratin-grp78 association was noted after co-immunoprecipitation of K8/18 from HT29 detergent solubilized cell lysates, and appears to involve non-posttranslationally modified grp78. The grp78-K8/18 association is induced by culturing cells in the presence of tunicamycin or after glucose starvation. K8/18-bound grp78 can be dissociated by Mg-ATP and the association can be reconstituted in vitro using purified grp78, then redissociated again by Mg-ATP. Binding of grp78 occurs preferentially with K8, and when reconstituted does not depend on the posttranslational modification state of K8/18. Co-incubation of K8/18 with hsp70 and grp78 shows preferential association with hsp70. Our results demonstrate a direct association of grp78 with K8 under conditions that induce grp78 expression. | lld:pubmed |
| pubmed-article:9409741 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9409741 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9409741 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9409741 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9409741 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:9409741 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:9409741 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9409741 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9409741 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:9409741 | pubmed:issn | 0014-5793 | lld:pubmed |
| pubmed-article:9409741 | pubmed:author | pubmed-author:PriceDD | lld:pubmed |
| pubmed-article:9409741 | pubmed:author | pubmed-author:LiaoJJ | lld:pubmed |
| pubmed-article:9409741 | pubmed:author | pubmed-author:PRATTC WCW | lld:pubmed |
| pubmed-article:9409741 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9409741 | pubmed:day | 17 | lld:pubmed |
| pubmed-article:9409741 | pubmed:volume | 417 | lld:pubmed |
| pubmed-article:9409741 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9409741 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9409741 | pubmed:pagination | 316-20 | lld:pubmed |
| pubmed-article:9409741 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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| pubmed-article:9409741 | pubmed:meshHeading | pubmed-meshheading:9409741-... | lld:pubmed |
| pubmed-article:9409741 | pubmed:year | 1997 | lld:pubmed |
| pubmed-article:9409741 | pubmed:articleTitle | Association of glucose-regulated protein (grp78) with human keratin 8. | lld:pubmed |
| pubmed-article:9409741 | pubmed:affiliation | Clontech Laboratories Inc., Palo Alto, CA 94303, USA. | lld:pubmed |
| pubmed-article:9409741 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9409741 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:9409741 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
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