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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1997-8-7
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pubmed:abstractText |
Recent studies have shown that patients with schizophrenia who have an adolescent-symptom onset (before age 21) have a worse clinical course and greater frequency of cerebral abnormalities than those with an adult-onset (after age 25). However, little is known about the neuropsychological functioning of these groups. A comprehensive neuropsychological examination was administered to groups of patients with schizophrenia with either an adolescent- or adult symptom-onset and a healthy control group. The adolescent-onset group performed worse than the adult-onset and control groups, particularly on measures of memory and executive function. The adult-onset group also performed worse than the controls, but to a lesser extent than did the adolescent-onset group. Results are discussed with reference to hypotheses that adolescent-onset schizophrenia represents a distinct neurodevelopmental disease entity.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0894-878X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
107-12
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9150511-Adolescent,
pubmed-meshheading:9150511-Adult,
pubmed-meshheading:9150511-Chronic Disease,
pubmed-meshheading:9150511-Cognition Disorders,
pubmed-meshheading:9150511-Delirium, Dementia, Amnestic, Cognitive Disorders,
pubmed-meshheading:9150511-Female,
pubmed-meshheading:9150511-Humans,
pubmed-meshheading:9150511-Male,
pubmed-meshheading:9150511-Mental Recall,
pubmed-meshheading:9150511-Neuropsychological Tests,
pubmed-meshheading:9150511-Prognosis,
pubmed-meshheading:9150511-Schizophrenia,
pubmed-meshheading:9150511-Schizophrenic Psychology
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pubmed:year |
1997
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pubmed:articleTitle |
Cognitive deficits distinguish patients with adolescent- and adult-onset schizophrenia.
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pubmed:affiliation |
Department of Psychology, University of Tulsa, Oklahoma, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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