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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1997-4-4
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pubmed:abstractText |
Although propofol (2-6 di-isopropylphenol) is commonly used to induce and maintain anesthesia and sedation for surgery, systematic hypotension and reduced cardiac output can occur in patients with or without intrinsic cardiac disease. The effect of propofol on myocyte contractility after the development of congestive heart failure (CHF) remains unknown. This study tested the hypothesis that propofol would have direct effects on myocyte contractile function in both healthy and CHF cardiac myocyte preparations.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0003-3022
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
86
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
649-59
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:9066332-Adrenergic beta-Agonists,
pubmed-meshheading:9066332-Anesthetics, Intravenous,
pubmed-meshheading:9066332-Animals,
pubmed-meshheading:9066332-Cardiac Pacing, Artificial,
pubmed-meshheading:9066332-Cardiotonic Agents,
pubmed-meshheading:9066332-Cells, Cultured,
pubmed-meshheading:9066332-Heart Failure,
pubmed-meshheading:9066332-Heart Ventricles,
pubmed-meshheading:9066332-Hypnotics and Sedatives,
pubmed-meshheading:9066332-Isoproterenol,
pubmed-meshheading:9066332-Myocardial Contraction,
pubmed-meshheading:9066332-Myocardium,
pubmed-meshheading:9066332-Propofol,
pubmed-meshheading:9066332-Receptors, Adrenergic, beta,
pubmed-meshheading:9066332-Sensitivity and Specificity,
pubmed-meshheading:9066332-Swine,
pubmed-meshheading:9066332-Ventricular Function, Left
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pubmed:year |
1997
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pubmed:articleTitle |
Negative and selective effects of propofol on isolated swine myocyte contractile function in pacing-induced congestive heart failure.
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pubmed:affiliation |
Department of Anesthesia and Perioperative Medicine, Medical University of South Carolina, Charleston 29425-2207, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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