Linked Life Data

8507472

Source:http://linkedlifedata.com/resource/pubmed/id/8507472

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1993-7-9
pubmed:abstractText
Chronic suppurative otitis media often ensues in patients treated with irradiation against a head and neck tumor. In an experimental study, rats were exposed to irradiation to evaluate the sensitivity of the middle ear to an accumulated irradiation dose of 20-45 Gy. Observed otomicroscopically, all animals appeared to have normal tympanic membranes and no fluid developed in the middle ear space. Ten days after the irradiation, minor structural changes had occurred in the pars flaccida. The keratinizing epithelium had thickened and mitoses were seen histologically. The lamina propria was edematous and contained polymorphonuclear cells and macrophages. The middle ear mucosa from all other tissue sites appeared normal. Six months after irradiation only minor changes in the pars flaccida were evident: the lamina propria was thin and inelastic and macrophages were present in the stroma. It is inferred from this study that the middle ear of the rat is relatively resistant to irradiation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0937-4477
pubmed:author
pubmed:issnType
Print
pubmed:volume
250
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
92-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Structural changes in the middle ear tissues of the rat after fractionated irradiation.
pubmed:affiliation
Department of Anatomy, University of Umeå, Sweden.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't