|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
1993-6-7
|
|
pubmed:abstractText |
In the rat four-vessel occlusion model with 30 minutes of ischemia most agents have failed to be of benefit when given after ischemia. Because postischemia administration is more clinically relevant, we evaluated the antioxidant LY231617 (2,6-bis(1,1-dimethylethyl)-4-[[(1-ethyl)amino]methyl]phenol hydrochloride]) when administered after 30 minutes of four-vessel occlusion.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
0039-2499
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
24
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
716-22; discussion 722-3
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:8488528-Animals,
pubmed-meshheading:8488528-Antioxidants,
pubmed-meshheading:8488528-Blood-Brain Barrier,
pubmed-meshheading:8488528-Brain Ischemia,
pubmed-meshheading:8488528-Butylated Hydroxytoluene,
pubmed-meshheading:8488528-Cell Survival,
pubmed-meshheading:8488528-Cells, Cultured,
pubmed-meshheading:8488528-Disease Models, Animal,
pubmed-meshheading:8488528-Dose-Response Relationship, Drug,
pubmed-meshheading:8488528-Drug Evaluation, Preclinical,
pubmed-meshheading:8488528-Hippocampus,
pubmed-meshheading:8488528-Hydrogen Peroxide,
pubmed-meshheading:8488528-Lipid Peroxidation,
pubmed-meshheading:8488528-Male,
pubmed-meshheading:8488528-Neurons,
pubmed-meshheading:8488528-Rats,
pubmed-meshheading:8488528-Rats, Wistar
|
|
pubmed:year |
1993
|
|
pubmed:articleTitle |
The antioxidant LY231617 reduces global ischemic neuronal injury in rats.
|
|
pubmed:affiliation |
Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285-0814.
|
|
pubmed:publicationType |
Journal Article,
Comparative Study,
In Vitro
|
