Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1993-9-16
pubmed:abstractText
Bacterial ascending from the cervix may infect the membranes and amniotic fluid, contributing to their premature rupture. In the present in vitro study, isolated amniotic membranes were exposed to different concentrations of disintegrated bacterial cells. Collagenolysis was estimated by the ratio of acid-soluble/insoluble hydroxyproline. The amniotic membrane proteins were separated by electrophoresis after incubation with 14C proline and disintegrated bacterial cells. The proportion of soluble hydroxyproline increased with the bacterial concentration used, and the radioactivity decreased in proteins of the 30- to 80-kD range. The data support the notion that bacteria contain collagenolytic enzymes affecting human amniotic membranes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0378-7346
pubmed:author
pubmed:issnType
Print
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
21-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Collagenolytic effect of disintegrated bacterial cell extracts on the human amniotic membrane at term pregnancy.
pubmed:affiliation
Department of Obstetrics and Gynaecology, Sahlgrenska University Hospital, Göteborg, Sweden.
pubmed:publicationType
Journal Article, In Vitro, Research Support, Non-U.S. Gov't