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pubmed-article:8331901pubmed:abstractTextExtracellular matrix remodeling after tissue injury involves both cell-cell and cell-matrix interactions. Integrins are matrix receptors that play a central role in such interactions, and transforming growth factor-beta (TGF-beta) is known to be a strong modulator of their expression. Our previous work has shown that in the anti-thymocyte serum-induced model of glomerulonephritis in the rat, elevated glomerular production of TGF-beta is a causal factor in matrix accumulation. Here we present data on the expression and distribution of glomerular beta 1 integrins in experimental glomerulonephritis.lld:pubmed
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pubmed-article:8331901pubmed:articleTitleCoordinated expression of beta 1 integrins and transforming growth factor-beta-induced matrix proteins in glomerulonephritis.lld:pubmed
pubmed-article:8331901pubmed:affiliationDivision of Nephrology, University of Utah School of Medicine, Salt Lake City.lld:pubmed
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