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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1993-8-12
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pubmed:abstractText |
The authors assessed the role of positron emission tomography (PET) with fluorine-18 fluorodeoxyglucose (FDG) in differentiation of benign from malignant focal pulmonary abnormalities seen on chest radiographs. Fifty-one patients underwent FDG PET scanning. Focal abnormalities at radiography included solitary pulmonary nodules (n = 38), pulmonary masses (n = 5), and poorly marginated infiltrates or opacities (n = 8). Proof of diagnosis was obtained by means of transbronchial biopsy (n = 21), open lung biopsy (n = 14), percutaneous needle biopsy (n = 14), or cytologic evaluation of sputum (n = 1). A nodule in one patient had been radiographically stable for at least 8 years. Quantitative analysis was performed by calculation of a standardized uptake ratio (SUR). Thirty-three malignant lesions had a mean SUR (+/- 1 standard deviation) of 6.5 +/- 2.9. Eighteen benign lesions had a mean SUR of 1.7 +/- 1.2. For a benign lesion with SUR of 2.5 or less, specificity of FDG PET was 100%, while sensitivity was 89%. These results suggest that FDG PET is accurate in differentiation of benign from malignant focal pulmonary abnormalities.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0033-8419
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
188
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
487-90
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8327702-Adult,
pubmed-meshheading:8327702-Aged,
pubmed-meshheading:8327702-Deoxyglucose,
pubmed-meshheading:8327702-Female,
pubmed-meshheading:8327702-Fluorine Radioisotopes,
pubmed-meshheading:8327702-Fluorodeoxyglucose F18,
pubmed-meshheading:8327702-Humans,
pubmed-meshheading:8327702-Lung Diseases,
pubmed-meshheading:8327702-Lung Neoplasms,
pubmed-meshheading:8327702-Male,
pubmed-meshheading:8327702-Middle Aged,
pubmed-meshheading:8327702-Tomography, Emission-Computed
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pubmed:year |
1993
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pubmed:articleTitle |
Focal pulmonary abnormalities: evaluation with F-18 fluorodeoxyglucose PET scanning.
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pubmed:affiliation |
Department of Radiology, Duke University Medical Center, Durham, NC 27710.
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pubmed:publicationType |
Journal Article
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