|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
8
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|
pubmed:dateCreated |
1994-8-23
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|
pubmed:abstractText |
Nicorandil, a potent antianginal agent characterized as a potassium channel opener, could produce cerebrovascular dilation in in vitro studies. Our aim was to investigate the pharmacologic response to the topical application of nicorandil on the vasomotor tone of pial vessels in vivo. To elucidate its mechanism, we also studied the inhibitory action of methylene blue and glibenclamide against nicorandil-induced vasodilation.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Aug
|
|
pubmed:issn |
0039-2499
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
25
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1644-50
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8042218-Administration, Topical,
pubmed-meshheading:8042218-Animals,
pubmed-meshheading:8042218-Arterioles,
pubmed-meshheading:8042218-Benzopyrans,
pubmed-meshheading:8042218-Cromakalim,
pubmed-meshheading:8042218-Dimethyl Sulfoxide,
pubmed-meshheading:8042218-Dogs,
pubmed-meshheading:8042218-Glyburide,
pubmed-meshheading:8042218-Methylene Blue,
pubmed-meshheading:8042218-Microcirculation,
pubmed-meshheading:8042218-Niacinamide,
pubmed-meshheading:8042218-Nicorandil,
pubmed-meshheading:8042218-Nitroglycerin,
pubmed-meshheading:8042218-Pia Mater,
pubmed-meshheading:8042218-Pyrroles,
pubmed-meshheading:8042218-Vasodilation,
pubmed-meshheading:8042218-Vasodilator Agents,
pubmed-meshheading:8042218-Venules
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pubmed:year |
1994
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pubmed:articleTitle |
Mechanisms of vasodilation of cerebral vessels induced by the potassium channel opener nicorandil in canine in vivo experiments.
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|
pubmed:affiliation |
Department of Anesthesiology and Critical Care Medicine, Gifu University School of Medicine, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|
