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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
1993-4-8
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pubmed:abstractText |
Thirty-five patients with an inoperable or non-resectable oesophageal carcinoma were treated with external radiotherapy to a maximum dose of 60 Gy followed by a booster irradiation by means of intraluminal brachytherapy at a low dose rate (40-112 cGy/h). For this extra irradiation, which lasted 20-36 h, a catheter with a thickness of 3 mm was introduced through the nose. This treatment could be carried out without sedation. The total radiation dose after the combination therapy amounted to 65-75 Gy. Of the 35 patients, 17 were pretreated with dilatation or laser therapy. The palliative effect after the external and internal irradiation was very good; only one patient still had minor dysphagia 6 weeks after the treatment. Transient irradiation oesophagitis occurred in 16 patients. In three patients, a secondary benign stenosis developed. The median duration of survival was 11 months, the 2-year survival rate was 10%. A comparison of these results with a historical control group treated only with external irradiation shows that the duration of survival of these patients appears to be increased during the first 45 weeks.
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pubmed:commentsCorrections | |
pubmed:language |
dut
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0028-2162
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
27
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pubmed:volume |
137
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
465-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7680440-Adult,
pubmed-meshheading:7680440-Aged,
pubmed-meshheading:7680440-Aged, 80 and over,
pubmed-meshheading:7680440-Brachytherapy,
pubmed-meshheading:7680440-Esophageal Neoplasms,
pubmed-meshheading:7680440-Female,
pubmed-meshheading:7680440-Humans,
pubmed-meshheading:7680440-Iridium Radioisotopes,
pubmed-meshheading:7680440-Male,
pubmed-meshheading:7680440-Middle Aged,
pubmed-meshheading:7680440-Palliative Care,
pubmed-meshheading:7680440-Radiotherapy, High-Energy,
pubmed-meshheading:7680440-Radiotherapy Dosage
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pubmed:year |
1993
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pubmed:articleTitle |
[Combination external and internal radiotherapy for esophageal carcinoma: a new prospect].
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pubmed:affiliation |
Afd. Radiotherapie, Academisch Ziekenhuis, Leiden.
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pubmed:publicationType |
Journal Article,
English Abstract
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