Linked Life Data

7534018

Source:http://linkedlifedata.com/resource/pubmed/id/7534018

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1995-4-13
pubmed:abstractText
We have examined 216 consecutive surgical specimens of patients with chronic pharmacoresistant temporal lobe epilepsy. Neoplasms were detected in 75 cases (34.7%). All but two of these tumors were of low histopathological grade (WHO-grade I or II). There were 34 gangliogliomas, 17 pilocytic astrocytomas, 9 oligodendrogliomas, 6 fibrillary astrocytomas, and 6 dysembryoplastic neuroepithelial tumors. Fifty-one specimens contained non-neoplastic focal lesions and an additional 13 cases had both tumors and non-neoplastic focal lesions within the same specimen. The most frequent non-neoplastic focal lesions were microscopic glioneuronal hamartias (32 cases), glioneuronal hamartomas (7 cases) and vascular malformations (13 cases). The hippocampal formation was structurally well preserved in 71 specimens and in 51 of these (71.8%) there was Ammon's horn sclerosis. The findings document that intractable temporal lobe epilepsy is associated with significant structural alterations in the great majority of patients.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0070-4113
pubmed:author
pubmed:issnType
Print
pubmed:volume
78
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
438-42
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
[Morphological findings in temporal lobe epilepsy: experience with 216 consecutive surgical specimens].
pubmed:affiliation
Institut für Neuropathologie, Universität Bonn.
pubmed:publicationType
Journal Article, English Abstract