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pubmed-article:7518621pubmed:abstractTextWe have proved that iNOS is regulated by induction of transcription. The induction of iNOS mRNA requires synthesis of an intermediary protein(s) and probably involves action of a protein kinase or kinases. We have cloned and sequenced a 1.7-kilobase pair fragment from the 5'-flanking region of the iNOS gene and proved that this region contains a promoter which confers inducibility of iNOS by LPS and IFN-gamma.lld:pubmed
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pubmed-article:7518621pubmed:articleTitlePromoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon-gamma and bacterial lipopolysaccharide.lld:pubmed
pubmed-article:7518621pubmed:affiliationDepartment of Medicine, Cornell University Medical College, New York, NY.lld:pubmed
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pubmed-article:7518621pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
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