| pubmed-article:7489410 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7489410 | lifeskim:mentions | umls-concept:C0039194 | lld:lifeskim |
| pubmed-article:7489410 | lifeskim:mentions | umls-concept:C1705165 | lld:lifeskim |
| pubmed-article:7489410 | lifeskim:mentions | umls-concept:C0205360 | lld:lifeskim |
| pubmed-article:7489410 | lifeskim:mentions | umls-concept:C0936012 | lld:lifeskim |
| pubmed-article:7489410 | lifeskim:mentions | umls-concept:C0392762 | lld:lifeskim |
| pubmed-article:7489410 | lifeskim:mentions | umls-concept:C2700061 | lld:lifeskim |
| pubmed-article:7489410 | lifeskim:mentions | umls-concept:C1515655 | lld:lifeskim |
| pubmed-article:7489410 | pubmed:issue | 12 | lld:pubmed |
| pubmed-article:7489410 | pubmed:dateCreated | 1996-1-2 | lld:pubmed |
| pubmed-article:7489410 | pubmed:abstractText | Although it is presumed that the integration of HIV-1 into the genome of infected CD4+ T lymphocytes allows viral persistence, there has been little direct evidence that CD4+ T cells with integrated provirus function as a latent reservoir for HIV-1 in infected individuals. Using resting CD4+ T-cell populations of extremely high purity and a novel assay that selectively and unambiguously detects integrated HIV-1, we show that resting CD4+ T cells harbouring integrated provirus are present in some infected individuals. However, these cells do not accumulate within the circulating pool of resting CD4+ T cells in the early stages of HIV-1 infection and do not accumulate even after prolonged periods in long-term survivors of HIV-1 infection. These results suggest that because of viral cytopathic effects and/or host effector mechanisms, productively infected CD4+ T cells do not generally survive for long enough to revert to a resting memory state in vivo. | lld:pubmed |
| pubmed-article:7489410 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7489410 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7489410 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7489410 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7489410 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7489410 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7489410 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7489410 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7489410 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:7489410 | pubmed:issn | 1078-8956 | lld:pubmed |
| pubmed-article:7489410 | pubmed:author | pubmed-author:SchwartzDD | lld:pubmed |
| pubmed-article:7489410 | pubmed:author | pubmed-author:SilicianoR... | lld:pubmed |
| pubmed-article:7489410 | pubmed:author | pubmed-author:FinziDD | lld:pubmed |
| pubmed-article:7489410 | pubmed:author | pubmed-author:MargolickJJ | lld:pubmed |
| pubmed-article:7489410 | pubmed:author | pubmed-author:ChouT JTJ | lld:pubmed |
| pubmed-article:7489410 | pubmed:author | pubmed-author:ChadwickKK | lld:pubmed |
| pubmed-article:7489410 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7489410 | pubmed:volume | 1 | lld:pubmed |
| pubmed-article:7489410 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7489410 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7489410 | pubmed:pagination | 1284-90 | lld:pubmed |
| pubmed-article:7489410 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:7489410 | pubmed:meshHeading | pubmed-meshheading:7489410-... | lld:pubmed |
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| pubmed-article:7489410 | pubmed:meshHeading | pubmed-meshheading:7489410-... | lld:pubmed |
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| pubmed-article:7489410 | pubmed:meshHeading | pubmed-meshheading:7489410-... | lld:pubmed |
| pubmed-article:7489410 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7489410 | pubmed:articleTitle | In vivo fate of HIV-1-infected T cells: quantitative analysis of the transition to stable latency. | lld:pubmed |
| pubmed-article:7489410 | pubmed:affiliation | Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA. | lld:pubmed |
| pubmed-article:7489410 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7489410 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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