Linked Life Data

7273671

Source:http://linkedlifedata.com/resource/pubmed/id/7273671

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1981-11-18
pubmed:abstractText
Forty-seven patients with confirmed TCA overdoses were thoroughly evaluated with regard to clinical and electrocardiographic findings. In 22 patients plasma levels of the primary TCA and the desmethyl metabolite were determined. We found that both neurologic and cardiovascular complications were common, but independent of each other. While plasma levels of the parent of TCA compound correlated best with the neurologic disturbances, cardiac abnormalities were more related to the desmethyl metabolite level. Although plasma levels correlate with the clinical findings, sufficient overlap between normal and abnormal levels and findings exist that we do not feel that routine measurement of plasma levels is clinically useful at this time.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0009-9309
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
599-613
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Tricyclic antidepressant overdose: clinical and pharmacologic observations.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.