Linked Life Data

7139867

Source:http://linkedlifedata.com/resource/pubmed/id/7139867

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1983-1-7
pubmed:abstractText
It has previously been observed that protease inhibitors suppress radiation transformation in vitro. In the experiments reported here, it was observed that a 24 h treatment with the protease inhibitor antipain at five days post-irradiation was sufficient to significantly suppress radiation transformation. Comparable experiments performed with cycloheximide, an inhibitor of protein synthesis, showed that this metabolic inhibitor could suppress radiation transformation when present immediately following the X-ray exposure but not when present for one day at five days post-irradiation. These results suggest that antipain is suppressing an ongoing cellular process occurring in response to X-irradiation.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0143-3334
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1093-5
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Antipain, but not cycloheximide, suppresses radiation transformation when present for only one day at five days post-irradiation.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.