Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1981-1-29
pubmed:abstractText
While Computerized Tomographic (CT) scans have been a valuable asset to radiotherapy treatment planning, their role in the critical assessment of tumour response has been less well defined. Recent refinements in radiotherapy treatment techniques have intensified the need for non-invasive methods to evaluate the local control of inaccessible neoplasms. In this study, 20 cases in which both pre- and post-treatment CT scans were available up to 27 months post-therapy were reviewed. The majority of the patients had pancreatic carcinoma. In both pre- and post-therapy scans, the tumour volume was calculated from contours outlined on sequential CT slices. These interpretations were compared with surgical findings, clinical course and patient survival. The rate of the primary tumour regression had little bearing on the clinical outcome. However, there was CT scan evidence of initial local tumour stabilization or regression in > 80% of the cases. In addition, CT scan evidence of tumour progression was correlated with clinical progression in > 90% of the patients. This suggests that a growth delay analysis might be possible with the use of CT scans, at least for the evaluation of pancreatic carcinoma.
pubmed:grant
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0306-9443
pubmed:author
pubmed:issnType
Print
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
30-4
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Computerized tomography in the quantitative assessment of tumour response.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.