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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1983-3-11
|
| pubmed:abstractText |
Epicardial and left ventricular endocardial activation were assessed in 5 patients (aged 4 months to 9.5 years) with endocardial cushion defect (ECD) during surgical repair. Epicardial activation was recorded from 40 to 47 sites over the epicardium; left ventricular endocardial activation was measured at 3 sites immediately after institution of cardiopulmonary bypass. Compared with the reported activation sequence in normal hearts, the pattern of excitation in hearts of patients with ECD was abnormal; epicardial excitation began at the left ventricular diaphragmatic surface and spread laterally and anteriorly over the anterobasal left ventricle. It then merged with right ventricular wavefronts ending along the right ventricular anterior atrioventricular groove and outflow tract. Left ventricular endocardial activation also occurred earliest in the diaphragmatic segment of the left ventricle with later wavefronts recorded laterally and anteriorly. This study demonstrates, for the first time in human subjects, correlation between left ventricular epicardial and endocardial activation in patients with ECD. The data indicate that earliest endocardial and epicardial activation occurs at the left ventricular diaphragmatic segments of the heart, and are consistent with the known posterior and inferior displacement of the specialized atrioventricular conduction system in patients with ECD.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
0002-9149
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
15
|
| pubmed:volume |
51
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
277-81
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:6823837-Child,
pubmed-meshheading:6823837-Child, Preschool,
pubmed-meshheading:6823837-Electrocardiography,
pubmed-meshheading:6823837-Electrophysiology,
pubmed-meshheading:6823837-Endocardial Cushion Defects,
pubmed-meshheading:6823837-Endocardium,
pubmed-meshheading:6823837-Female,
pubmed-meshheading:6823837-Heart,
pubmed-meshheading:6823837-Heart Conduction System,
pubmed-meshheading:6823837-Heart Septal Defects,
pubmed-meshheading:6823837-Humans,
pubmed-meshheading:6823837-Infant,
pubmed-meshheading:6823837-Male
|
| pubmed:year |
1983
|
| pubmed:articleTitle |
Epicardial and endocardial activation in patients with endocardial cushion defect.
|
| pubmed:publicationType |
Journal Article
|