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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4588
|
| pubmed:dateCreated |
1983-3-24
|
| pubmed:abstractText |
The mutant mouse pearl, characterized by its hypopigmentation, has a specific functional defect in a sensory system--the retina. The intact pearl mouse has reduced sensitivity in the dark-adapted condition. Normal sensitivity is restored by isolation and superfusion of the retina with bicarbonate-buffered Ringer solution, suggesting that the retinal expression of the pearl mutation depends on a diffusible substance. The pearl phenotype is described as a possible model for human congenital stationary night blindness.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Mar
|
| pubmed:issn |
0036-8075
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
4
|
| pubmed:volume |
219
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1085-7
|
| pubmed:dateRevised |
2008-11-21
|
| pubmed:meshHeading |
pubmed-meshheading:6600521-Animals,
pubmed-meshheading:6600521-Dark Adaptation,
pubmed-meshheading:6600521-Disease Models, Animal,
pubmed-meshheading:6600521-Mice,
pubmed-meshheading:6600521-Mice, Mutant Strains,
pubmed-meshheading:6600521-Night Blindness,
pubmed-meshheading:6600521-Retina,
pubmed-meshheading:6600521-Vision, Ocular
|
| pubmed:year |
1983
|
| pubmed:articleTitle |
Discrete visual defects in pearl mutant mice.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|