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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1984-11-21
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pubmed:abstractText |
Ten cases of sporadic cerebral amyloid angiopathy (CAA) were seen as intracranial hemorrhage. CAA was seen as a stroke or catastrophic intracranial hemorrhage in all cases. CAA complicated by intracranial hemorrhage carried a high mortality; 9 of 10 patients died in spite of aggressive medical or surgical treatment. Senile dementia of Alzheimer's type was an associated finding in only 1 patient. Computed tomographic scanning in 4 patients initially was not diagnostic for hemorrhage. Lambda chains and amyloid P protein were demonstrated in the areas of amyloid angiopathy immunocytochemically. The pathogenesis of hemorrhage in CAA could be either increased fragility of amyloid-laden blood vessels or rupture of microaneurysms. Surgical treatment of intracranial hemorrhage in CAA should therefore be undertaken with caution.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0364-5134
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
321-9
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:6385824-Aged,
pubmed-meshheading:6385824-Amyloid,
pubmed-meshheading:6385824-Amyloidosis,
pubmed-meshheading:6385824-Brain,
pubmed-meshheading:6385824-Cerebral Arterial Diseases,
pubmed-meshheading:6385824-Cerebral Arteries,
pubmed-meshheading:6385824-Cerebral Hemorrhage,
pubmed-meshheading:6385824-Female,
pubmed-meshheading:6385824-Humans,
pubmed-meshheading:6385824-Immunoenzyme Techniques,
pubmed-meshheading:6385824-Immunoglobulins,
pubmed-meshheading:6385824-Intracranial Aneurysm,
pubmed-meshheading:6385824-Male,
pubmed-meshheading:6385824-Middle Aged,
pubmed-meshheading:6385824-Serum Amyloid P-Component
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pubmed:year |
1984
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pubmed:articleTitle |
Cerebral amyloid angiopathy causing intracranial hemorrhage.
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pubmed:publicationType |
Journal Article
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