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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1982-7-22
|
| pubmed:abstractText |
Ketotifen-induced histamine release from human leucocytes is independent of extracellular calcium and does not require metabolic energy. Furthermore, histamine release is accompanied by a loss of cellular cytoplasmic contents. This suggests that the mechanism of ketotifen-induced histamine release at high concentrations is non-specific and is similar to that of clemastine, a typical H1 antagonist.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0020-5915
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
68
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
176-8
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:6176557-Calcium,
pubmed-meshheading:6176557-Clemastine,
pubmed-meshheading:6176557-Cytoplasm,
pubmed-meshheading:6176557-Dose-Response Relationship, Immunologic,
pubmed-meshheading:6176557-Histamine Release,
pubmed-meshheading:6176557-Humans,
pubmed-meshheading:6176557-Ketotifen,
pubmed-meshheading:6176557-Leukocytes
|
| pubmed:year |
1982
|
| pubmed:articleTitle |
The mechanism of ketotifen-induced histamine release from human peripheral leucocytes.
|
| pubmed:publicationType |
Journal Article
|