Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1984-12-6
|
pubmed:abstractText |
Seventy-five percent of the amino acid sequence of simian virus 40 (SV40) large T antigen is identical to that of the large T antigen of the human papovavirus, BK virus (BKV). Cross-reactivity between BKV T antigen and monoclonal antibodies directed against SV40 T antigen was studied by immunofluorescence, an enzyme immunoassay, immunoprecipitation of radiolabeled extracts, and Western blotting. BKV T antigen was found to be recognized by two monoclonal antibodies, PAb 416 and 430, which react with two distinct sites toward the amino terminus of SV40 large T antigen. These two sites may correspond to two hydrophilic regions of shared amino acid sequence which exist toward the amino termini of the T antigens.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0042-6822
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
30
|
pubmed:volume |
138
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
379-85
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:6093375-Amino Acid Sequence,
pubmed-meshheading:6093375-Antibodies, Monoclonal,
pubmed-meshheading:6093375-Antibody Specificity,
pubmed-meshheading:6093375-Antigens, Viral, Tumor,
pubmed-meshheading:6093375-BK Virus,
pubmed-meshheading:6093375-Cross Reactions,
pubmed-meshheading:6093375-Fluorescent Antibody Technique,
pubmed-meshheading:6093375-Immunoenzyme Techniques,
pubmed-meshheading:6093375-Molecular Weight,
pubmed-meshheading:6093375-Polyomavirus,
pubmed-meshheading:6093375-Simian virus 40
|
pubmed:year |
1984
|
pubmed:articleTitle |
Cross-reaction of BK virus large T antigen with monoclonal antibodies directed against SV40 large T antigen.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|