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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1986-1-21
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pubmed:abstractText |
The thermogenic capacity of brown adipose tissue has been investigated in I-strain mice to determine whether this tissue could play a role in the lower efficiency of food utilization reported in this strain of mice. (1) As compared with C57BL mice (a control strain), interscapular-brown-adipose-tissue weight and lipid percentage were decreased by 40% and 13% respectively in I-strain mice. (2) Mitochondrial protein content and cytochrome c oxidase activity were similar in the two strains, but the number of mitochondrial GDP-binding sites and uncoupling-protein content were increased by 2-fold in I-strain mice. (3) Fatty acid synthetase and citrate-cleavage enzyme (units/mg of protein) were 3-fold higher in the brown adipose tissue of I-strain mice. These results indicate that I-strain mice possess a very active brown adipose tissue. This enhanced capacity of energy dissipation in brown adipose tissue could contribute to the decreased capacity of I-strain mice to store adipose tissue.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/4074335-1008874,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4074335-1253787,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4074335-13035501,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4074335-14889324,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4074335-165754,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4074335-23106,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4074335-383147,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4074335-388439,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4074335-3967754,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4074335-3973745,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4074335-4146798,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4074335-4291912,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4074335-476529,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4074335-477972,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4074335-520559,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4074335-551265,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4074335-6135416,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4074335-6141788,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4074335-6319201,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4074335-638848,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4074335-6409080,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4074335-6466314,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4074335-667688,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4074335-6720944,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4074335-6839011,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4074335-6882379,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4074335-7093244,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4074335-7115345,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4074335-7195009,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4074335-942051
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0264-6021
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
231
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
761-4
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:4074335-ATP Citrate (pro-S)-Lyase,
pubmed-meshheading:4074335-Adipose Tissue, Brown,
pubmed-meshheading:4074335-Animals,
pubmed-meshheading:4074335-Fatty Acid Synthetase Complex,
pubmed-meshheading:4074335-Hot Temperature,
pubmed-meshheading:4074335-Lipids,
pubmed-meshheading:4074335-Malate Dehydrogenase,
pubmed-meshheading:4074335-Male,
pubmed-meshheading:4074335-Mice,
pubmed-meshheading:4074335-Mice, Inbred Strains,
pubmed-meshheading:4074335-Mitochondria,
pubmed-meshheading:4074335-Proteins
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pubmed:year |
1985
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pubmed:articleTitle |
Thermogenic and lipogenic activities in brown adipose tissue of I-strain mice.
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pubmed:publicationType |
Journal Article,
Comparative Study
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