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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1977-8-25
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pubmed:abstractText |
Tracheal intubation of viable Pseudomonas aeruginosa ATCC 19660 into the lungs of mice had no significant effect on the animals even with administration of organisms as high as 5.0 X 10(9) CFU. Animals treated with a single injection of an antineoplastic drug were, however, susceptible to bacterial challenge into the lungs. LD50 values of 4.1 X 10(7), 4.8 X 10(7), and 1.0 X 10(8) CFU were obtained when animals were simultaneously infected and treated with methotrexate, vincristine sulfate, or cytosine arabinoside, respectively.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0008-4166
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
823-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:406029-Animals,
pubmed-meshheading:406029-Antineoplastic Agents,
pubmed-meshheading:406029-Cytarabine,
pubmed-meshheading:406029-Female,
pubmed-meshheading:406029-Immunity,
pubmed-meshheading:406029-Intubation, Intratracheal,
pubmed-meshheading:406029-Lethal Dose 50,
pubmed-meshheading:406029-Lung Diseases,
pubmed-meshheading:406029-Methotrexate,
pubmed-meshheading:406029-Mice,
pubmed-meshheading:406029-Pseudomonas Infections,
pubmed-meshheading:406029-Pseudomonas aeruginosa,
pubmed-meshheading:406029-Vincristine
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pubmed:year |
1977
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pubmed:articleTitle |
Experimental pulmonary infection of mice by tracheal intubation of Pseudomonas aeruginosa: the use of antineoplastic agents to overcome natural resistance.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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