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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1985-6-11
|
| pubmed:abstractText |
Volume regulation in the red cell depends on the balance between the osmotic swelling pressure contributed by the polyvalent anions 2,3-DPG and haemoglobin, and the counterbalancing osmotic pressure provided by extracellular Na+. Although changes in 2,3-DPG have been identified in some cases, increases in the electrodiffusional leak of Na+ and K+ are most likely responsible for the disorders of volume regulation leading to haemolytic anaemia. The current challenge is to identify the membrane proteins and/or lipids which play a key role in passive transport of the monovalent cations.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0308-2261
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
14
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
89-103
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:3886241-Anemia, Hemolytic,
pubmed-meshheading:3886241-Cell Membrane Permeability,
pubmed-meshheading:3886241-Centrifugation, Density Gradient,
pubmed-meshheading:3886241-Erythrocyte Membrane,
pubmed-meshheading:3886241-Erythrocytes,
pubmed-meshheading:3886241-Hemolysis,
pubmed-meshheading:3886241-Humans,
pubmed-meshheading:3886241-Osmolar Concentration
|
| pubmed:year |
1985
|
| pubmed:articleTitle |
Haemolytic anaemia associated with increased cation permeability.
|
| pubmed:publicationType |
Journal Article,
Review
|