Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
77-78
|
| pubmed:dateCreated |
1979-1-26
|
| pubmed:abstractText |
Growth of wildtype Escherichia coli was inhibited by azaserine. There was an inverse relationship between the initial rate of uptake of phenylalanine and the azaserine concentration. Moderately azaserine-resistant mutants exhibited an initial rate that was similar to that of an aroP mutant, but highly azaserine-resistant mutants exhibited little, if any, uptake of phenylalanine. All of the azaserine-resistant organisms tested harboured a mutation in the aroP+ gene. However, resistance to the antibiotic was not due solely to this lesion.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0026-2633
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
19
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
181-90
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:362130-Aspartic Acid,
pubmed-meshheading:362130-Azaserine,
pubmed-meshheading:362130-Drug Resistance, Microbial,
pubmed-meshheading:362130-Escherichia coli,
pubmed-meshheading:362130-Glucose,
pubmed-meshheading:362130-Mutation,
pubmed-meshheading:362130-Phenylalanine,
pubmed-meshheading:362130-Stereoisomerism,
pubmed-meshheading:362130-Transduction, Genetic
|
| pubmed:year |
1977
|
| pubmed:articleTitle |
Studies on the modes of action of azaserine in Escherichia coli. Mechanism of resistance to azaserine.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
|